GABAB receptor system modulates mitragynine-induced conditioned place preference in rats
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چکیده
منابع مشابه
5-HT2A Serotonin Receptor Density in Adult Male Rats’ Hippocampus after Morphine-based Conditioned Place Preference
Introduction: A close interaction exists between the brain opioid and serotonin (5-HT) neurotransmitter systems. Brain neurotransmitter 5-HT plays an important role in the regulation of reward-related processing. However, a few studies have investigated the potential role of 5-HT2A receptors in this behavior. Therefore, the aim of the present study was to assess the influence of...
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Background: Consumption of chronic morphine induces neuro-inflammation and addictive seeking behavior. Ginger (Zingiber Officinale Roscoe), a well-known spice plant, has been used traditionally in the treatment of a wide variety of ailments. It has been shown that ginger has anti-inflammatory, anti-oxidative and antinociceptive properties. However, its influences on morphine-induced addictive b...
متن کامل[Electroacupuncture suppresses morphine--induced conditioned place preference (CPP) in rats].
OBJECTIVE To examine the effects produced by electroacupuncture (EA) of different frequencies on the expression of morphine conditioned place preference (CPP) in rats. METHODS SD rats were given 4 days consecutive trials in a computerized three-chamber "unbiased" CPP apparatus. Twenty-four hours later, the time spent on drug-pairing compartment of the rat was examined. Rats trained with CPP p...
متن کاملSertraline influence on morphine-induced conditioned place preference in rats.
UNLABELLED Serotonine reuptake inhibitors are an important pharmacological arsenal for treating major depression, a severe disease with poorly understood pathogenic mechanisms. Also, little is known about the action of antidepressants on reward system, the function of which is severely affected in this disorder. AIM To assess the influence of sertraline on brain reward system by conditioned p...
متن کاملEffects of adenosine receptor agonists and antagonists in amphetamine-induced conditioned place preference test in rats.
The influence of adenosine receptor agonists and antagonists on amphetamine-induced conditioned place preference (CPP) was examined in male Wistar rats. Selective adenosine A1 receptor agonist, CPA, significantly reduced the acquisition of CPP induced by amphetamine. NECA (A2/A1 adenosine receptor agonist) produced similar effect, but selective A2 adenosine receptor agonist CGS 21680, attenuate...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2016
ISSN: 1662-5102
DOI: 10.3389/conf.fncel.2016.36.00090